The DESIGNER Approach Helps Decipher the Hypoglycemic Bioactive Principles of Artemisia dracunculus (Russian Tarragon)
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چکیده
منابع مشابه
Potential application of Russian Tarragon (Artemisia dracunculus L.) in health and sports
Background Tarragon is a spice herb with a long history of culinary and medical use. There exist two cultivars of this species: French Tarragon is used as a spice in cuisine and Russian Tarragon (RT) has been used medically in Russia and middle Asia, mainly to treat gastrointestinal disorders. However, recent studies also reported possible antidiabetic and hypoglycemic activities. Ribnickyet al...
متن کاملEffective cytochrome P450 (CYP) inhibitors isolated from tarragon (Artemisia dracunculus).
Two effective cytochrome P450 (CYP) inhibitors were isolated from tarragon, Artemisia dracunculus. Their structures were spectroscopically identified as 2E,4E-undeca-2,4-diene-8,10-diynoic acid isobutylamide (1) and 2E,4E-undeca-2,4-diene-8,10-diynoic acid piperidide (2). Both compounds had dose-dependent inhibitory effects on CYP3A4 activity with IC50 values of 10.0 ± 1.3 µM for compound 1 and...
متن کاملThe effect of Russian Tarragon (artemisia dracunculus L.) on the plasma creatine concentration with creatine monohydrate administration
Background It has previously been shown that the plasma concentration of creatine following supplementation is influenced by extracellular concentrations of insulin and glucose, the form in which creatine is administered, and also the creatine concentration in the muscle cells. The common practice of raising insulin levels to increase initial uptake into muscle, by means of high amounts of gluc...
متن کاملThe effects of hydro-alcoholic extract of Artemisia dracunculus L. (Tarragon) on hematological parameters in mice
Introduction: Artemisia dracunculus L. (Tarragon) is one of the plants that uses as meal and remedy for a long time, and possesses many medicinal properties. In traditional medicine also has mentioned to its beneficial properties. A number of researches through in vitro and in vivo studies showed the pharmacological properties of this plant. This study was done for determining the effect of hyd...
متن کاملThe Synergic Effect of Artemisia Dracunculus (Tarragon) Extract and Aspirin (ASA) on Platelet Function
Background: Coagulation activity of platelets plays an important role in thrombosis formation, Atherosclerotic plaque establishment and cardiovascular disorders. ASA are using as an anti platelet activity drug for patients with Coronary Artery Disease (CAD). Using of plant extraction as a complementary medicine for these patients (CAD) is mostly recommended by traditional medicine specialist. ...
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2019
ISSN: 0163-3864,1520-6025
DOI: 10.1021/acs.jnatprod.9b00548